Some gut bacteria synthesize vitamin K, which affects blood clotting
doi:10.1016/S1474-4422(20)30173-3 169
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At 5 mg/mL, 10 units equals 0.5 mg, which is the second dose level in the standard escalation schedule
De-escalated neoadjuvant pertuzumab plus trastuzumab therapy with or without weekly paclitaxel in HER2positive, hormone receptor-negative, early breast cancer (WSG-ADAPT-HER2+/HR-): survival outcomes from a multicentre, open-label, randomised, phase 2 trial