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Study participants who took the Wegovy pill also improved their physical function and cardiovascular risk factors, including their BMI, glucose levels and lipid profile, Azar said

In obesity, hypertrophic expansion of adipocytes leads to hypoxia, oxidative stress, and the release of pro-inflammatory adipokines, thereby promoting insulin resistance and ectopic lipid deposition [31]

Drucker DJ (2022) GLP-1 physiology informs the pharmacotherapy of obesity

The gut-liver axis represents a complex and bidirectional relationship between the gastrointestinal tract and the liver, mediated by portal circulation, immune signals, and microbial interactions

These physical symptoms can indirectly impact mental wellbeing, causing distress, affecting sleep quality, and reducing overall quality of life