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When a small group of patients began taking a very tiny dose starting at 0.0675 mg, compared to the label-recommended 0.25 mg and increased it gradually, they were able to tolerate it better than the folks who started the usual dose and tried to escalate it in the typical way, says Alkhaddo

In animal studies, side effects have been minimal and mostly gastrointestinal

The two medications work through completely separate mechanisms

Tirzepatide is an injectable medication initially developed to manage type 2 diabetes

Diet Quality: Even though GLP-1 drugs reduce overall food intake, what you eat still matters

eating smaller meals and avoiding fatty foods may help Constipation: Staying hydrated and eating fiber-rich foods can provide relief Reduced appetite: Working with a clinician to ensure adequate nutrition is important The adjustment period and what to expect Side effects are often most noticeable when starting medication or increasing doses