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Patients with Crohn's disease who are considering or currently prescribed GLP-1 receptor agonists for diabetes or weight management should have comprehensive discussions with their gastroenterology team
Recent Developments In February 2026 , Pfizer announced positive Phase 2b trial results for its ultra-long-acting injectable GLP-1 (PF-08653944), demonstrating significant weight loss with monthly dosing
Recent studies suggest synergistic effects of H3K18 and H3K9 lactylation in regulating CD8 T-cell effector function [124], and H3K14 and H3K9 lactylation in promoting calcification in calcific aortic valve disease [125]
This promotes a more effective folding process that improves the use of oxygen
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