They were all large trials of 3,000 to 14,000 patients with similar baseline patient demographics: 30% to 45% were female, average age was between 54 and 66 years, baseline HbA1c was 7.7% to 8.8%, with the exception of the REWIND trial which enrolled a lower-risk population with better controlled T2DM (HbA1c, 7.3%) and a greater proportion of females (46%)
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Some people benefit from a single session for a quick boost, while others may opt for a series of weekly or bi-weekly infusions for more sustained effects, followed by maintenance sessions
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Redox imbalance can result in key events determining or associated with the onset and progression of the cardiovascular diseases, such as heart failure [12]