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The Department of Health and Social Care (DHSC) has warned that the shortage of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) will continue, with supply not expected to return to normal until at least the end of 2024

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doi: 10.1056/NEJMoa2004967 60 SridharVSBhattDLOdutayoASzarekMDaviesMJBanksPet al

10 Conclusion and perspectives DKD, a serious DM-related microvascular disorder, is pathologically defined by persistent hyperglycemia-triggered complex metabolic abnormalities, ultimately leading to glomerular filtration barrier destruction and tubulointerstitial injury (13, 132, 224)