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10.3390/toxins9110348 267 SilvaJ.Monge-FuentesV.GomesF.LopesK.Dos AnjosL.CamposG.et al (2015)

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Common Endpoints by Route Endpoint Skin firmness or smoothness Topical timeline 8-12 weeks Injectable framing Anecdotal

A double-blind placebo-controlled trial of NAC versus selenium versus selenium plus NAC versus placebo found significant improvements in all semen parameters with both NAC and selenium trialled singly, and additive effects when both were used together