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By directly donating an electron to these dangerous compoundssuch as hydrogen peroxide, superoxide anions, and hydroxyl radicalsglutathione effectively neutralizes them before they can inflict structural damage on the cell

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Critically, a study has shown that the levels of GSH, a key antioxidant, are significantly reduced in the AD brain and that the extent of this depletion correlates positively with the severity of cognitive impairment (43)

Discussion Different lines of evidence have recently highlighted the fructose impact on brain metabolic alterations [13, 23], but it remains unclear whether the observed sugar-induced adverse effects are limited exclusively to the period of increased intake or are persistent even when it is eliminated from the dietary regimen

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