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Many factors, such as age, diet, smoking, and some autoimmune conditions, also influence when the hair turns gray

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PubMed laboratory research record [PMID: 31486321] PubMed record related to this compound for laboratory literature review

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In March 2026, Structure reported 44-week topline data from the ACCESS II Phase 2 study, showing placebo-adjusted weight loss of up to 16.3%, which the company described as the highest efficacy demonstrated among oral GLP-1 receptor agonists at that time point