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Glucagon-like peptide-1 receptor agonists (GLP-1RA) and Diabetic Retinopathy Prepared by: Emily Short, PharmD, PGY-1 Pharmacy Resident, Boston Medical Center What is diabetic retinopathy
The compound is synthesized using glutamine, glycine, and cysteine amino acids
FDA-approved GLP-1 receptor agonists, such as Ozempic, Wegovy, and older drugs like liraglutide (Saxenda, Victoza) and dulaglutide (Trulicity), have revolutionized treatment by enabling: Better blood sugar control in type 2 diabetes patients Weight loss support through appetite regulation and delayed digestion Potential reduction in cardiovascular risk for some patients While these drugs have become increasingly popular for metabolic health care, they can come with side effects like gastrointestinal discomfort, and must be taken under medical supervision
Resveratrol gets more antioxidant genes expressed (superoxide dismutase, catalase, glutathione peroxidase) and thus encourages more activation of the Nrf2/ARE pathway