The GlyNAC combination (glycine + NAC) showed multi-system improvements in a 16-week RCT in older adults, including corrected glutathione deficiency, reduced oxidative stress, improved mitochondrial function, and enhanced physical performance
GHK-Cu has demonstrated a counterintuitive homeostatic property: it stimulates collagen production in atrophic skin while normalizing excessive collagen deposition in fibrotic tissue
Sikiric, P., Boban Blagaic, A., Strbe, S., Beketic Oreskovic, L., Oreskovic, I., Sikiric, S., Staresinic, M., Sever, M., Kokot, A., Jurjevic, I., Matek, D., Coric, L., Krezic, I., Tvrdeic, A., Luetic, K., Batelja Vuletic, L., Pavic, P., Mestrovic, T., Sjekavica, I.,
DEGs were identified using DESeq2 (v.1.36.0) based on an adjusted p-value threshold of 2
Senolytics: targeting senescent cells for age-associated diseases
It's generally well-tolerated