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It depends on your body and how low your B12 levels were

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555,556 Lifestyle modifications include head-up tilt sleeping, which elevates the head of the bed by 1030 to reduce nocturnal diuresis and improve morning orthostatic tolerance, and advising patients to avoid triggers such as prolonged standing, sudden postural changes, high ambient temperatures, and large meals that may exacerbate symptoms

However, it's important to note that these shots are not a standalone solution for weight management