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Side effect comparison: Nausea: Tirzepatide rates range from 12% to 33% depending on dose, comparable to cagrilintide Vomiting: Tirzepatide higher than cagrilintide Diarrhea: Similar rates Injection site reactions: Cagrilintide significantly higher than tirzepatide Fatigue: Tirzepatide fatigue is commonly reported, comparable to cagrilintide Some researchers are exploring cagrilintide combined with tirzepatide for potentially enhanced effects

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Aldosterone induced by AngII promoting the reabsorption of sodium and water from the kidney, can increase water retention, and norepinephrine secretion via positive feedback from the sympathetic end of the anterior membrane, eventually leading to an increase in BP

A study of women, published in Sage Journals in June, found that the drugs impact on hormones could decrease sexual drive

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