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The lack of targeted delivery exacerbates off-target effects and limits therapeutic efficacy, particularly in patients with comorbidities requiring polypharmacy (Karantas et al., 2024)

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Allium Vegetables: Garlic, onions, and leeks are excellent sources of the sulfur compounds needed for glutathione synthesis

GAPDH was used as a reference gene

A broader review of glutathione for skin reached a similar, cautious conclusion, noting limited high-quality evidence overall (a narrative review of the safety and efficacy of glutathione supplementation for skin lightening)

These free radicals are among the major causes of premature ageing