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Avoid restricting: Restricting food often creates a scarcity effect, which can perpetuate binge cycles

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The STEP-HFpEF trial showed that among patients with obesity and HFpEF, once-weekly semaglutide may be beneficial in terms of weight loss and quality of life

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Various dual/triple agonists for glucagon-like peptide-1 receptor (GLP-1R), which also target the gastric inhibitory peptide receptor and glucagon receptor, have recently been explored to increase treatment efficacy for both diabetes and obesity in the clinical setting [9, 10]