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Thus, cholinergic neurotransmission and ACh-dependent regulation of non-neuronal cells employ ThDP coenzyme function for ACh synthesis and non-coenzyme action of thiamine in ACh signaling
Definition Box Signal Peptide: A short peptide sequence that triggers downstream cellular responses (gene expression, enzyme activation, cytokine release) by interacting with receptors or transport proteins rather than by being incorporated into larger structures
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