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Under conditions of metabolic stress, it migrates to the cell nucleus, where it activates a suite of genes governed by AMPK (AMP-activated protein kinase), the master cellular energy sensor
These effects are particularly relevant for tendons and ligaments, which are inherently limited by poor vascular supply
This boost in energy is particularly beneficial for workout routines, allowing individuals to push beyond their limits without feeling exhausted afterwards
doi:10.1016/j.envint.2019.105237 Soga M, Gaston KJ, Yamaura Y
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