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[5] In Latin America, about 40 percent are estimated to be affected, and this may be as high as 80 percent in parts of Africa and Asia

We restricted the study cohorts to patients with a diagnosis of type 2 diabetes and without use of any of the two drug classes being compared for the past 365 days, aged 18 years (65 years for Medicare), and with at least 12 months of continuous insurance enrollment before cohort entry

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selection should be individualized based on indication, efficacy, tolerability, and patient-specific factors