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Outras estratgias exploradas incluram a reduo da depurao renal de compostos baseados em GLP-1 ou exendina, por meio da fuso covalente do peptdeo a protenas plasmticas de grande estabilidade, como a albumina (albiglutida) ou o domnio Fc de IgG (dulaglutida)
These findings suggest that GLP-1RAs may have therapeutic potential beyond diabetes and obesity, particularly in the treatment of addictions to palatable foods, alcohol, and drugs
Detailed analysis and synthesis of the extracted data
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