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Prescribing it for weight loss is off-label, and demand for weight loss has contributed to supply problems for people who need it for diabetes

Benefits: Longer duration of action compared to cyanocobalamin May require less frequent dosing Preferred for patients with certain medical conditions Population-Specific Formulation Preferences The choice between cyanocobalamin and hydroxocobalamin depends on individual patient needs

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GLP-1 agonists are generally well tolerated with GI side effects such as nausea, vomiting, and diarrhea predominating