SCFAs: The Microbial Molecules That Tell the Brain to Stop Eating SCFAs like butyrate, propionate, and acetate: activate GLP-1 reduce cravings stabilize energy support insulin sensitivity balance blood sugar regulate appetite hormones Reference Butyrate & Appetite Hormone Regulation (Scientific Reports, 2019) Low SCFAs = hunger dysregulation
However, sustained palpitations, chest pain, or fainting require immediate medical evaluation
LAURIE SUND: Yeah, well, first of all, these medications are life-changing
Mechanism of thymidylate synthase inhibition by methotrexate in human neoplastic cell lines and normal human myeloid progenitor cells
Ive been seeing the same thing, especially in my psychiatric patients
Some contain caffeine or fiber that modestly support appetite control, but none match prescription drugs