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Patients on insulin or sulfonylureas should consider MOTS-c a glucose-modifying agent until formal interaction data exist
Results from the PIVENS trial showed that oral administration of the anti-oxidant vitamin E improved liver dysfunction and the pathological conditions of NASH [17]
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To name a few, the succination of GPX4 by intracellular fumarate aggregation could sensitize cancer cells to ferroptosis inducers (FINs), whereas the alkylation of GPX4 could serve as a route for class II FINs to induce ferroptosis [57,58]
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