34, 35, 36, 37, 38, 39 However, it is unknown if GLP-1R occurs on PSCs in normal pancreas, on activated PSCs in AP or CP or if this does occur, whether the GLP-1R agonists affect the PSC signaling cascade, PSC growth or ability to release inflammatory mediators
J.DudekD.et al
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Even patients who had already used another GLP-1 medication saw better results with tirzepatide
Additional benefits are expected from double and triple receptor agonists, but specific human clinical trials are needed