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Where patient-level incidence was available, the proportion with 1 AE ranged from 035% in treatment arms and 1046% in controls

This is particularly important for patients with complex medical histories or those who have required individualized dose titration schedules

However, it's crucial to acknowledge that individual responses to medication can vary, and factors like lifestyle modifications and underlying health conditions play a role in overall outcome

[5] Pharmacokinetic interactions are relatively limited because topiramate is neither a strong cytochrome-P450 inducer nor inhibitor at customary doses

References for this information: 1.International Journal of Dermatology, August 2021, pages 1013-1018 2

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