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In diabetes and obesity, growth factor-associated signaling in the brain deteriorates and energy use in the cerebral cortex decreases simultaneously with pro-inflammatory changes, while GLP-1RAs improve neuronal growth and repair, reduce inflammation and apoptosis, as well as oxidative stress [31]
Jun 2012;61(3):230-234
I will link to those so you can take a deeper dive on the whys of HRT And why we're often starting the estrogen progesterone is because that's laying the groundwork for the improved insulin sensitivity
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