Acknowledgements This work was supported by the Research Fund of Ghent University, Belgium, grant BOF08/GOA/004 and BOF14/GOA/010 and Fonds Wetenschappelijk Onderzoek Vlaanderen (grant FWO14/PDO/067)
This reduces strain on healthcare systems and expands global access

Heres your action plan: Step 1: Stop the medication immediately As soon as you see that positive pregnancy test Dont wait for a doctors appointment to stop Dont take one more dose while you figure things out Stop today Step 2: Call your prescribing doctor The doctor who prescribed your GLP-1 needs to know Theyll document when you stopped and your last dose They may need to transition you to alternative medications (if using GLP-1 for diabetes) Step 3: Contact your OB/GYN or schedule first prenatal visit Schedule appointment within 1-2 weeks Bring documentation: medication name, dose, start date, last injection date Your OB/GYN will establish appropriate monitoring plan They may recommend earlier or additional ultrasounds Step 4: Dont panicseriously These medications havent been clearly linked to birth defects in the limited human data we have so far, but we also dont have enough high-quality studies to say theyre definitely safe

2,3 Preliminary studies have demonstrated positive results in this approach, yet the mechanism by which IGF-1 treatments might correct for insulin resistance clinically remains unclear
In March 2026, Aardvark Therapeutics announced that the US FDA had placed a full clinical hold on its investigational new drug application for ARD-101 related to the Companys previously announced voluntary pause
Increased Energy Levels: IV infusion vitamins can boost energy levels by replenishing crucial vitamins like B-complex, vitamin C, and magnesium