Adherence rates for oral formulations are typically 5-10% lower than injectables due to administration complexity and GI side effects (nausea, constipation, diarrhea)
Remember, the key to successful and sustainable weight loss lies in adopting healthy habits and making long-term lifestyle changes, rather than relying on quick fixes or shortcuts
Scientists have not given up on the drugs for these conditions, but they will need to pivot, focusing on new GLP-1 research questions spurred by the trials results
Physiological Reviews, 79 (2), 511 607
The increased production of acetyl-CoA is a direct contributor to the increased production of fatty acids and ultimately triglycerides and the consequent infiltration of fat in tissues, particularly the liver
Martina Lenzen-Schulte