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The reduced incretin effect of GIP in diabetic subjects may be due to the down-regulation of GIP receptor expression, which has been found in pancreatic islets of diabetic Zucker rats and reverted following correction of hyperglycemia [35]

But skipping it means starting every day in a protein hole thats hard to climb out of by dinner

Effects of dietary acetyl-L-Carnitine on meat quality and lipid metabolism in Arbor Acres broilers