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PubMed PMID 40789979 2025 review of musculoskeletal research noting broad preclinical findings but extremely limited human data

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2017 study reported improvements in aged mice that were sustained through the observation period, suggesting that senescent cell clearance produces durable benefits once senescent cells are eliminated, their pro-inflammatory SASP burden is removed, allowing tissue recovery that persists beyond the treatment window

Nevertheless, the evidence for antidepressants in tinnitus treatment is inconclusive

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