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SCFA deficits might also play a role: fecal levels of butyrate and other SCFAs are reported to be reduced in AD patients, which could exacerbate neuroinflammation by depriving microglia of anti-inflammatory signals [130]
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This review synthesizes current evidence regarding SGLT2 inhibitors and GLP-1 receptor agonists in DKD, examines their mechanisms and clinical outcomes, and highlights future research directions to address ongoing therapeutic needs
Overall, the market appears to be shifting toward specialized, next-generation therapies
Wegovy is a GLP-1 receptor agonist administered weekly by subcutaneous injection for chronic weight management in adults with obesity or overweight with comorbidities
He serves as a member of the editorial board for the Journal of Alzheimer's Disease and has published extensively in peer-reviewed scientific journals, including the Archives of Neurology , Neuroscience , and the Journal of Applied Nutrition
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