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Common causes of B12 deficiency can include: Limited dietary intake (common in strict vegan or vegetarian diets) Pernicious anemia, an autoimmune condition that prevents proper B12 absorption in the stomach Gastrointestinal surgeries that remove part of the stomach or small intestine Age-related declines in stomach acid production Long-term use of certain medications, such as metformin or proton pump inhibitors, which can reduce the bodys ability to properly absorb vitamin B12

One compound gaining attention in this space is 5-Amino-1MQ

Retatrutide has shown greater standalone weight loss

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In many regions it remains a research peptide and should only be used under medical supervision

Maintenance phase: After the loading phase, dosing typically drops to 2 mg every one to two weeks