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However, MR is mainly recruited under baseline and GR conditions under stress, since MR has a 10-fold higher affinity for CORT [53]

Since the successful birth of the first human infant from a cryopreserved oocyte in 1986, oocyte cryopreservation technology has achieved significant breakthroughs, thereby expanding the possibilities for clinical fertility preservation ( Oxidative stress plays a crucial role not only during the in vitro preservation stage but also in the reproductive decline associated with advanced maternal age ( in vitro fertilization technology, the influence of advanced maternal age on fertilization and preimplantation embryo development is relatively minor

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