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It didnt garner much interest in the medical world until the 1990s

& Goggins, M

Alternative diabetes medications include several classes with different mechanisms of action: SGLT2 inhibitors (such as dapagliflozin, empagliflozin, or canagliflozin) work by increasing urinary glucose excretion and offer cardiovascular and renal benefits

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However, recent reports suggest no significant risk in humans

This screening protects patient safety and ensures appropriate protocol design based on individual circumstances