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Gu et al

The metabolism of starch and sucrose (15 KOs), was also reduced in the AcM groups ( PYG , sucrose phosphorylase , GBE1 , glgA , UGP2 , glgC , malZ , INV , 6-phospho-beta-glucosidase , pgmB , celA , celB , scrA , bglX and inuJ ), together with the depletion of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), and with the biosynthesis of cofactors (31 KOs), including those involved in the metabolism of vitamins, such as thiamine ( adk , thiD , thiI and iscS ), riboflavin ( ribF ), pantothenate ( coaA , coaBC and coaE ), pyridoxine ( pdxK ) and folate ( DHFR , folC , folD , fhs , glyA and metK )

However, many patients do not present with either physiological symptoms, such as organ damage, or psychiatric conditions and still suffer from post-infectious chronic fatigue [1]

For example the reaction of cysteine with sugars in a Maillard reaction yields meat flavours

In gene therapy, nanoparticle carriers that encapsulate siRNA or miRNA can target and modulate the expression of drug-resistant genes, thereby enhancing chemotherapy sensitivity and immune activation