Published 2024-5-30 Background: Tamoxifen is commonly used in the treatment of hormonal-positive breast cancer
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Practical limitations of translating food-derived molecules into clinical therapies are to isolate pure molecules, to establish their potency and efficacy as individual or combined moieties in cell bioassays, to work out their pharmacokinetics in preclinical animal models, and then to manufacture them with excipients in pharmaceutical oral solid dosage forms at the correct dose levels for subsequent clinical testing