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10.1016/j.fertnstert.2022.04.003 Fertil Steril
Information regarding clinical outcomes after a switch within the GLP-1 RA class is limited
[15] This signal has not been confirmed in humans, but it is reflected in the prescribing information for approved GLP-1-based medicines such as semaglutide (see the UK Summary of Product Characteristics for Wegovy, available via the electronic Medicines Compendium)
This inhibition of endogenous GNE resulted in 70% reduction in GNE expression and 80% 2 reduction in total cellular sialylation 15
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