Anti-atherosclerosis Effects Atherosclerosis, a chronic inflammatory disorder of the arterial wall, involves several key contributors to its initiation and progression that can be favorably altered or attenuated by GLP-1 agonists
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From a pharmacokinetic perspective, besides increased gastric emptying, obesity has been suggested to modulate CYP gene expression, and increased fat mass may result in an increased Vd of lipophilic drugs
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