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In less critical scenarios, the safest approach is to wait for data
What if its deeper, rooted in the complex, invisible network that runs your bodyyour hormones
Grgic T et al
These approaches have led to significant weight loss with the dual GLP-1/glucagon receptor agonist survodutide (-13.5% with the 6-mg dose at 76 weeks in a phase 3 SYNCHRONIZE-1 trial) [16] , the dual GLP-1 receptor agonist and GIP antagonist Maridebart cafraglutide (known as MariTide) (-12.3% to -16.2% across different doses at 52 weeks in a phase 2 trial) [17] or the triple GLP-1/GIP/glucagon receptor agonist retatrutide (-24.2% with the 12-mg dose at 48 weeks in a phase 2 trial) [18]
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When side effects do occur, they are typically mild and may include temporary redness, itching, or sensitivity at the application or injection site
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