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The SURPASS-3 MRI substudy added another layer, showing tirzepatide actually reduced muscle fat infiltration across all doses, indicating improved muscle quality even as total muscle volume decreased
It is naturally produced by the body and also found in certain foods
IL-17 is mainly secreted by T helper 17 (Th17) cells, which are elevated in the bone marrow of OVX mice with low estrogen
Explanation of treatment and expected outcomes
Acknowledgements This work was supported by the National Natural Science Foundation of China (81371590, 30770602)
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