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GLP-1s like semaglutide and tirzepatide have proven wildly successful at helping treat type 2 diabetes, manage weight, and deliver a ton of other health benefits, such as improving heart health and reducing addictive behaviors like drinking

Pharmacol Res Perspect 3:e00136 Pai V, Paneerselvam A, Mukhopadhyay S et al (2014) A multicenter, prospective, randomized, double-blind study to evaluate the safety and efficacy of Saroglitazar 2 and 4 mg compared to pioglitazone 45 mg in diabetic dyslipidemia (PRESS V)

Subjects of the randomized controlled trial (RCT) are usually selected from relatively healthy individuals, patients with a history of MTC or pancreatitis may be excluded, RCT are not long enough to cause cancer AEs, and no RCT has tumor events as the primary outcome

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