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Other rare but serious complications include gallbladder disease, severe allergic reactions (rash, throat swelling, difficulty breathing), and thyroid concerns in patients with personal or family history of thyroid cancer

Since the primary treatment is limited to symptomatic treatment, the development of new therapeutic agent is highly desired

In particular, poly(I:C), a synthetic viral RNA mimic, increased GLP-1 release in mice [1-2]

For some patients, Contrave may help: Feel satisfied with smaller portions Reduce frequent feelings of hunger Decrease cravings for high-calorie or highly processed foods Make it easier to stick with a reduced-calorie eating plan Support gradual, long-term weight loss These effects don't happen overnight, and they don't replace healthy habits

10.1248/cpb.c13-00556 50 Jia-LinZ.Yuan-YuanL.Wen-LiangY.Fu-JiaL.Zi-XiaT.Xin-MeiX.et al (2017)

Athletes should consult their sport's governing body and anti-doping authority before considering any peptide supplement