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IGF-1 acts as a mediator of GHs effects on growth and development, particularly in skeletal tissues and muscles

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On the contrary, GSTs exhibiting a cysteine as catalytic residue catalyze the opposite reaction (deglutathionylation) and exhibit thiol-transferase or reductase activities

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Notably, IL-6 enhanced the cell index of 12Z cells relative to the untreated group, aligning with previous research linking elevated IL-6 levels to increased proliferation of endometriotic cells in the late stages of the disease 28