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The N-terminal tails of histones are targets for multiple modifications, including phosphorylation, methylation, acetylation, ubiquitination, poly ADP ribosylation, and sumoylation
Mutations in GLUD1 and HNF4A each account for approximately 5% of individuals with FHI
Critical Reviews in Clinical Laboratory Sciences
Across different organs, protein-bound lysine is methylated to form -N-trimethyllysine in a reaction catalyzed by specific lysine methyltransferases that use S-adenosyl-methionine (derived from methionine) as a methyl donor
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