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Youle M, et al
These reductions translate into billions of dollars in savings for American consumers
The nigrostriatal pathway, part of the basal ganglia motor circuit, becomes impaired as dopamine levels drop, leading to characteristic motor symptoms such as bradykinesia, rigidity, and resting tremor ( Clinical manifestations of PD are highly heterogeneous (Tolosa et al., 2021), adding complexity to the development of therapeutic strategies
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