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Although variable between mice, SKO mice administered with liraglutide released very high levels of insulin in response to glucose, 8 times higher than those of PBS-treated SKO mice and 40 times higher than those of liraglutide-treated WT mice

12 The key is hitting protein targets, not carb levels

What to eat instead for enhanced GLP-1 activity: skip the sugary processed foods and aim for mostly whole, nutrient-dense foods that help the body maintain steady blood sugar levels

While natural GLP-1 rarely causes problems, pharmaceutical GLP-1 agonists commonly cause gastrointestinal side effects including nausea, vomiting, diarrhea, and constipation, particularly during dose escalation

Tirzepatide (Mounjaro for type 2 diabetes, Zepbound for weight management) is a dual GIP/GLP-1 receptor agonist that has generated questions about potential effects on sexual function