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Ipamorelin is a growth hormone releasing peptide (GHRP) that works synergistically with CJC 1295 to boost HGH levels without significantly increasing hunger or cortisol levels

Nucleic Acids Res 46:W510W513

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Stopping medication may increase the likelihood of weight regain if lifestyle habits are not maintained

Researchers became interested in combining these peptides when early studies revealed their complementary pharmacokinetics: Ipamorelin peptide provides an immediate GH pulse (peaking within 40 minutes), while CJC-1295 sustains release over several hours