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The delay of any of the factors in gastric emptying causes disorganization or reduced frequency of antral contractions and thus delayed GE
Report suspected adverse reactions through the MHRA Yellow Card Scheme to support ongoing medication safety monitoring
Fatigue during tirzepatide treatment may relate to caloric restriction from appetite suppression rather than a direct drug effect
We used the proportion of patients covered as it is less affected by the length of the grace period compared with time-to-event analyses, and takes not only discontinuation but also reinitiation of treatment into account [31]
PMC12852416 (2025) 6
The study also has limitations, including a 12-month follow-up, which may not reflect the complete clinical impact of T2D a chronic condition requiring long-term treatment
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