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Reconstitution and Preparation: AOD-9604 for injection is typically supplied as a lyophilized (freeze-dried) powder requiring reconstitution with bacteriostatic water before injection

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Real-time PCR was carried out on a LightCycler (Roche, Germany) using SYBR Premix EX Taq reagent (TaKaRa, Shiga, Japan)

FcRn engages the constant IgG Fc part, which via a flexible hinge region is linked to two fragment antigen binding (Fab) arms that contain the variable (V) regions specific for a given antigen

So to answer the question - can vitamin B12 deficiency cause varicose veins - the answer is, yes