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In clinical trials of semaglutide injection for type 2 diabetes mellitus (T2DM), cholelithiasis was reported in 1.5% and 0.4% of patients-treated with semaglutide 0.5 mg and 1 mg subcutaneous injection, respectively

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doi: 10.1038/s41591-021-01584-3 82 GersteinHCColhounHMDagenaisGRDiazRLakshmananMPaisPet al

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Extended Data Figure 4 Effects of binding pocket mutations on potency of NAMs

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References Pickart L, et al

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