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The Effects of Postprandial Walking on the Glucose Response after Meals with Different Characteristics
However, it is critical to distinguish between biological activity and therapeutic efficacy: these biomarker changes did not translate into any measurable clinical benefit, and should therefore be interpreted as evidence of limited central engagement rather than as support for the prevention-dominant hypothesis
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In this trial, once-weekly cagrilintide-semaglutide for 68 weeks in adults with overweight or obesity was highly effective and led to substantial and clinically meaningful weight loss, the authors concluded
TRIUMPH-4, reported in late 2025, focused on adults with obesity and knee osteoarthritis
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